Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands

Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands

The Arenaviridae family, together with the Bunyaviridae and Orthomyxoviridae families, is one of the three negative-stranded RNA viral families that encode an endonuclease in their genome. The endonuclease domain is at the N-terminus of the L protein, a multifunctional protein that includes the RNA-...

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Bibliographic Details
Main Authors: Magali Saez-Ayala, Elsie Laban Yekwa, Mauro Carcelli, Bruno Canard, Karine Alvarez, François Ferron
Format: Article
Language:English
Published: International Union of Crystallography 2018-03-01
Series:IUCrJ
Subjects:
Arenaviridae
endonucleases
Lymphocytic choriomeningitis virus
LCMV
diketo acids
compound optimization
metal chelation
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252518001021

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http://scripts.iucr.org/cgi-bin/paper?S2052252518001021

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