Differential Activation in Amygdala and Plasma Noradrenaline during Colorectal Distention by Administration of Corticotropin-Releasing Hormone between Healthy Individuals and Patients with Irritable Bowel Syndrome.

Differential Activation in Amygdala and Plasma Noradrenaline during Colorectal Distention by Administration of Corticotropin-Releasing Hormone between Healthy Individuals and Patients with Irritable Bowel Syndrome.

Irritable bowel syndrome (IBS) often comorbids mood and anxiety disorders. Corticotropin-releasing hormone (CRH) is a major mediator of the stress response in the brain-gut axis, but it is not clear how CRH agonists change human brain responses to interoceptive stimuli. We tested the hypothesis that...

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Bibliographic Details
Main Authors: Yukari Tanaka, Motoyori Kanazawa, Michiko Kano, Joe Morishita, Toyohiro Hamaguchi, Lukas Van Oudenhove, Huynh Giao Ly, Patrick Dupont, Jan Tack, Takuhiro Yamaguchi, Kazuhiko Yanai, Manabu Tashiro, Shin Fukudo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4957789?pdf=render

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http://europepmc.org/articles/PMC4957789?pdf=render

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