Transcriptomic Analysis Identifies Candidate Genes and Gene Sets Controlling the Response of Porcine Peripheral Blood Mononuclear Cells to Poly I:C Stimulation

Transcriptomic Analysis Identifies Candidate Genes and Gene Sets Controlling the Response of Porcine Peripheral Blood Mononuclear Cells to Poly I:C Stimulation

Polyinosinic-polycytidylic acid (poly I:C), a synthetic dsRNA analog, has been demonstrated to have stimulatory effects similar to viral dsRNA. To gain deep knowledge of the host transcriptional response of pigs to poly I:C stimulation, in the present study, we cultured and stimulated peripheral blo...

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Bibliographic Details
Main Authors: Jiying Wang, Yanping Wang, Huaizhong Wang, Haifei Wang, Jian-Feng Liu, Ying Wu, Jianfeng Guo
Format: Article
Language:English
Published: Oxford University Press 2016-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
polyinosinic-polycytidylic acid (poly I:C)
peripheral blood mononuclear cells (PBMC)
RNA-seq
differentially expressed (DE) genes
pigs
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.028290

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http://g3journal.org/lookup/doi/10.1534/g3.116.028290

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