Targeting BCL2-Proteins for the Treatment of Solid Tumours
Due to their central role in the regulation of apoptosis, the antiapoptotic BCL2-proteins are highly promising targets for the development of novel anticancer treatments. To this end, several strategies have been developed to inhibit BCL2, BCL-XL, BCL-w, and MCL1. While early clinical trials in haem...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2014-01-01
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| Series: | Advances in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/943648 |