Contribution of the <it>PALB2</it> c.2323C>T [p.Q775X] Founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent

Contribution of the <it>PALB2</it> c.2323C>T [p.Q775X] Founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent

<p>Abstract</p> <p>Background</p> <p>The <it>PALB2</it> c.2323C>T [p.Q775X] mutation has been reported in at least three breast cancer families and breast cancer cases of French Canadian descent and this has been attributed to common ancestors. The number...

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Bibliographic Details
Main Authors: Tischkowitz Marc, Sabbaghian Nelly, Hamel Nancy, Pouchet Carly, Foulkes William D, Mes-Masson Anne-Marie, Provencher Diane M, Tonin Patricia N
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Medical Genetics
Subjects:
<it>PALB2</it>
p.Q775X
p.Q775*
Hereditary breast cancer
Breast cancer risk
Ovarian cancer
Founder mutations
French Canadians
Online Access:http://www.biomedcentral.com/1471-2350/14/5

Internet

http://www.biomedcentral.com/1471-2350/14/5

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