PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
<p>Abstract</p> <p>Background</p> <p>Huntington disease (HD) is an inherited neurodegenerative disease caused by an abnormal expansion of a CAG repeat in the huntingtin <it>HTT </it>(<it>HD</it>) gene. The primary genetic determinant of the age a...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-05-01
|
| Series: | Molecular Neurodegeneration |
| Online Access: | http://www.molecularneurodegeneration.com/content/6/1/32 |