Activation of Akt/mTOR pathway is associated with poor prognosis of nasopharyngeal carcinoma.

Nasopharyngeal carcinoma (NPC) is a malignant tumor of the head and neck region, which frequently occurs in Southeast Asia, especially in the south of China. It is known that the mammalian target of rapamycin (mTOR) pathway plays a central role in regulating cellular functions, including proliferati...

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Bibliographic Details
Main Authors: Weiyuan Wang, Qiuyuan Wen, Lina Xu, Guiyuan Xie, Jiao Li, Jiadi Luo, Shuzhou Chu, Lei Shi, Donghai Huang, Jinghe Li, Songqing Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25165983/pdf/?tool=EBI