Impact of interleukin-6 gene polymorphisms and its interaction with obesity on osteoporosis risk in Chinese postmenopausal women

Abstract Aims To investigate the association of four single-nucleotide polymorphisms (SNPs) of the IL-6 gene with osteoporosis (OST) susceptibility. Methods PCR restriction fragment length polymorphism (PCR–RFLP) was carried out for SNPs detection. Generalized multifactor dimensionality reduction (G...

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Bibliographic Details
Main Authors: Ya-Feng Ji, Xuesheng Jiang, Wei Li, Xingtao Ge
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Environmental Health and Preventive Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12199-019-0803-y