Autophagy Declines with Premature Skin Aging resulting in Dynamic Alterations in Skin Pigmentation and Epidermal Differentiation

Autophagy Declines with Premature Skin Aging resulting in Dynamic Alterations in Skin Pigmentation and Epidermal Differentiation

Autophagy is a membrane traffic system that provides sustainable degradation of cellular components for homeostasis, and is thus considered to promote health and longevity, though its activity declines with aging. The present findings show deterioration of autophagy in association with premature ski...

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Bibliographic Details
Main Authors: Daiki Murase, Ayumi Kusaka-Kikushima, Akira Hachiya, Rachel Fullenkamp, Anita Stepp, Asuka Imai, Mizuki Ueno, Keigo Kawabata, Yoshito Takahashi, Tadashi Hase, Atsushi Ohuchi, Shuhei Nakamura, Tamotsu Yoshimori
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy
melanosome
keratinocyte
skin
hyperpigmentation
aging
Online Access:https://www.mdpi.com/1422-0067/21/16/5708

Internet

https://www.mdpi.com/1422-0067/21/16/5708

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