Vitamin D as a Novel Regulator of Tumor Metabolism: Insights on Potential Mechanisms and Implications for Anti-Cancer Therapy

Vitamin D as a Novel Regulator of Tumor Metabolism: Insights on Potential Mechanisms and Implications for Anti-Cancer Therapy

1,25-dihydroxyvitamin D3 [1,25(OH)2D3], the bioactive form of vitamin D, has been shown to possess significant anti-tumor potential. While most studies so far have focused on the ability of this molecule to influence the proliferation and apoptosis of cancer cells, more recent data indicate that 1,2...

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Bibliographic Details
Main Authors: Mohamed A. Abu el Maaty, Stefan Wölfl
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:International Journal of Molecular Sciences
Subjects:
vitamin D
cancer
metabolism
autophagy
AMPK (AMP-activated protein kinase)
mTOR (Mammalian target of rapamycin)
TXNIP (Thioredoxin-interacting protein)
p53
HIF1a (Hypoxia-inducible factor 1a)
c-Myc
Online Access:https://www.mdpi.com/1422-0067/18/10/2184

Internet

https://www.mdpi.com/1422-0067/18/10/2184

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