High Rates of Genome Rearrangements and Pathogenicity of Shigella spp.

High Rates of Genome Rearrangements and Pathogenicity of Shigella spp.

Shigella are pathogens originating within the Escherichia lineage but frequently classified as a separate genus. Shigella genomes contain numerous insertion sequences (ISs) that lead to pseudogenisation of affected genes and an increase of non-homologous recombination. Here, we study 414 genomes of...

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Bibliographic Details
Main Authors: Zaira Seferbekova, Alexey Zabelkin, Yulia Yakovleva, Robert Afasizhev, Natalia O. Dranenko, Nikita Alexeev, Mikhail S. Gelfand, Olga O. Bochkareva
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
Shigella
Escherichia coli
pathogens
recombination
E3 ubiquitin-ligases
IS
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.628622/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.628622/full

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