Folate-Functionalized Mesoporous Silica Nanoparticles as a Liver Tumor-Targeted Drug Delivery System to Improve the Antitumor Effect of Paclitaxel

The aim of this study was to prepare and characterize an innovative hepatocellular carcinoma-targeted therapeutic drug delivery system based on folate-PEG-mesoporous silica nanoparticles (FA-PEG-MSNs) loaded with paclitaxel (PTX). In vitro cell experiments and an in vivo antitumor efficacy study dem...

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Bibliographic Details
Main Authors: Xiaoyan Xu, Chao Wu, Andi Bai, Xuan Liu, Huiling Lv, Ying Liu
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2017/2069685