Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel disease

Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel disease

Host-microbial cross-talk plays a crucial role in maintenance of gut homeostasis. However, how microbiota-derived metabolites, e.g., butyrate, regulate functions of neutrophils in the pathogenesis of inflammatory bowel disease (IBD) remains elusive. We sought to investigate the effects of butyrate o...

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Bibliographic Details
Main Authors: Gengfeng Li, Jian Lin, Cui Zhang, Han Gao, Huiying Lu, Xiang Gao, Ruixin Zhu, Zhitao Li, Mingsong Li, Zhanju Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Gut Microbes
Subjects:
inflammatory bowel disease
butyrate
neutrophils
neutrophil extracellular traps
inflammatory mediators
Online Access:http://dx.doi.org/10.1080/19490976.2021.1968257

Internet

http://dx.doi.org/10.1080/19490976.2021.1968257

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