A 16-Channel Automated Rotometer System for Reliable Measurement of Turning Behavior in 6-Hydroxydopamine Lesioned and Transplanted Rats

Unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway in rats result in a massive dopamine (DA) denervation of the ipsilateral striatum. Such animals have proven extremely useful as a model for the study of Parkinson's disease, an idiopathic neurodegenerative disorder of humans. Ext...

Full description

Bibliographic Details
Main Authors: John L. Hudson, Dennis R. Levin, Barry J. Hoffer
Format: Article
Language:English
Published: SAGE Publishing 1993-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979300200608