In Vivo Biodistribution of Respirable Solid Lipid Nanoparticles Surface-Decorated with a Mannose-Based Surfactant: A Promising Tool for Pulmonary Tuberculosis Treatment?

In Vivo Biodistribution of Respirable Solid Lipid Nanoparticles Surface-Decorated with a Mannose-Based Surfactant: A Promising Tool for Pulmonary Tuberculosis Treatment?

The active targeting to alveolar macrophages (AM) is an attractive strategy to improve the therapeutic efficacy of ‘old’ drugs currently used in clinical practice for the treatment of pulmonary tuberculosis. Previous studies highlighted the ability of respirable solid lipid nanop...

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Bibliographic Details
Main Authors: Eleonora Truzzi, Thais Leite Nascimento, Valentina Iannuccelli, Luca Costantino, Eliana Martins Lima, Eliana Leo, Cristina Siligardi, Magdalena Lassinantti Gualtieri, Eleonora Maretti
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nanomaterials
Subjects:
tuberculosis
in vivo administration
lipid nanoparticles
alveolar macrophages
active targeting
Online Access:https://www.mdpi.com/2079-4991/10/3/568

Internet

https://www.mdpi.com/2079-4991/10/3/568

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