The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent

Interferon alpha/beta (IFN-α/β) is a critical mediator of protection against most viruses, with host survival frequently impossible in its absence. Many studies have investigated the pathways involved in the induction of IFN-α/β after virus infection and the resultant upregulation of antiviral IFN-s...

Full description

Bibliographic Details
Main Authors: Whitney C. Lane, Matthew D. Dunn, Christina L. Gardner, L. K. Metthew Lam, Alan M. Watson, Amy L. Hartman, Kate D. Ryman, William B. Klimstra, Christine A. Biron
Format: Article
Language:English
Published: American Society for Microbiology 2018-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/2/e00535-18