The Role of Nicotinamide in Cancer Chemoprevention and Therapy

The Role of Nicotinamide in Cancer Chemoprevention and Therapy

Nicotinamide (NAM) is a water-soluble form of Vitamin B3 (niacin) and a precursor of nicotinamide-adenine dinucleotide (NAD<sup>+</sup>) which regulates cellular energy metabolism. Except for its role in the production of adenosine triphosphate (ATP), NAD<sup>+</sup> acts as...

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Bibliographic Details
Main Authors: Ilias P. Nikas, Stavroula A. Paschou, Han Suk Ryu
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
niacinamide
nad<sup>+</sup> metabolism
sirt1
parp1
ontrac clinical trial
radiotherapy
non-melanoma skin cancer
actinic keratosis
chemotherapy resistance
cancer prevention
Online Access:https://www.mdpi.com/2218-273X/10/3/477

Internet

https://www.mdpi.com/2218-273X/10/3/477

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