Opposite effects of tissue inhibitor of metalloproteinases-1 (TIMP-1) over-expression and knockdown on colorectal liver metastases

<p>Abstract</p> <p>Background</p> <p>Tissue inhibitors of metalloproteinases (TIMPs) and the corresponding metalloproteinases are integral parts of the protease network and have been shown to be involved in cancer development and metastasis. Paradoxically, for TIMP-1, t...

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Bibliographic Details
Main Authors: Bandapalli Obul R, Paul Eva, Schirmacher Peter, Brand Karsten
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/5/14