Organ Culture Model of Aortic Valve Calcification

A significant amount of knowledge has been gained with the use of cell-based assays to elucidate the mechanisms that mediate heart valve calcification. However, cells used in these studies lack their association with the extra-cellular matrix or the influence of other cellular components of valve le...

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Bibliographic Details
Main Authors: Adrian H. Chester, Padmini Sarathchandra, Ann McCormack, Magdi H. Yacoub
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.734692/full