Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization

Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization

Abstract Background Dysfunction of the retinal pigment epithelium (RPE) is implicated in numerous forms of retinal degeneration. The readily accessible environment of the eye makes it particularly suitable for the transplantation of RPE cells, which can now be derived from autologous induced pluripo...

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Main Authors: Roni A. Hazim, Saravanan Karumbayaram, Mei Jiang, Anupama Dimashkie, Vanda S. Lopes, Douran Li, Barry L. Burgess, Preethi Vijayaraj, Jackelyn A. Alva-Ornelas, Jerome A. Zack, Donald B. Kohn, Brigitte N. Gomperts, April D. Pyle, William E. Lowry, David S. Williams
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Stem Cell Research & Therapy
Subjects:
Retinal pigment epithelium
Induced pluripotent stem cells
RPE cytoskeleton
Live-cell imaging
Phagocytosis
Online Access:http://link.springer.com/article/10.1186/s13287-017-0652-9

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http://link.springer.com/article/10.1186/s13287-017-0652-9

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