Epithelial vectorial ion transport in cystic fibrosis: Dysfunction, measurement, and pharmacotherapy to target the primary deficit
Cystic fibrosis patients display multi-organ system dysfunction (e.g. pancreas, gastrointestinal tract, and lung) with pathogenesis linked to a failure of Cl − secretion from the epithelial surfaces of these organs. If unmanaged, organ dysfunction starts early and patients experience chronic respira...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-06-01
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| Series: | SAGE Open Medicine |
| Online Access: | https://doi.org/10.1177/2050312120933807 |