Demethylmenaquinone Methyl Transferase Is a Membrane Domain-Associated Protein Essential for Menaquinone Homeostasis in Mycobacterium smegmatis

Demethylmenaquinone Methyl Transferase Is a Membrane Domain-Associated Protein Essential for Menaquinone Homeostasis in Mycobacterium smegmatis

The intracellular membrane domain (IMD) in mycobacteria is a spatially distinct region of the plasma membrane with diverse functions. Previous comparative proteomic analysis of the IMD suggested that menaquinone biosynthetic enzymes are associated with this domain. In the present study, we determine...

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Bibliographic Details
Main Authors: Julia Puffal, Jacob A. Mayfield, D. Branch Moody, Yasu S. Morita
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
demethylmenaquinone methyl transferase
membrane domain
menaquinone
metabolic homeostasis
Mycobacterium
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03145/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03145/full

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