Effect of silencing C-erbB-2 on esophageal carcinoma cell biological behaviors by inhibiting IGF-1 pathway activation

Abstract Objective C-erbB-2 has been confirmed to be an oncogene that participates in cell growth, differentiation and division of tumors. We are wondered if its silenced expression can exert an anti-tumor effect. Therefore, this study is conducted to investigate the mechanism of C-erbB-2 silencing...

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Bibliographic Details
Main Authors: Zhigao Niu, Wenping Zhang, Jialun Shi, Xiangdong Li, Hanlei Wu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-021-01540-9