Mathematical Modelling of Metabolic Regulation in Aging

The underlying cellular mechanisms that characterize aging are complex and multifaceted. However, it is emerging that aging could be regulated by two distinct metabolic hubs. These hubs are the pathway defined by the mammalian target of rapamycin (mTOR) and that defined by the NAD+-dependent deacety...

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Bibliographic Details
Main Authors: Mark T. Mc Auley, Kathleen M. Mooney, Peter J. Angell, Stephen J. Wilkinson
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Metabolites
Subjects:
Online Access:http://www.mdpi.com/2218-1989/5/2/232