Maternal schistosomiasis impairs offspring Interleukin-4 production and B cell expansion.

Epidemiological studies have identified a correlation between maternal helminth infections and reduced immunity to some early childhood vaccinations, but the cellular basis for this is poorly understood. Here, we investigated the effects of maternal Schistosoma mansoni infection on steady-state offs...

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Bibliographic Details
Main Authors: Diana Cortés-Selva, Lisa Gibbs, Andrew Ready, H Atakan Ekiz, Ryan O'Connell, Bartek Rajwa, Keke C Fairfax
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009260