Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis

Abstract Altered composition of gut bacteria and changes to the production of their bioactive metabolites, the short-chain fatty acids (SCFAs), have been implicated in the development of multiple sclerosis (MS). However, the immunomodulatory actions of SCFAs and intermediaries in their ability to in...

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Bibliographic Details
Main Authors: Stephanie Trend, Jonatan Leffler, Anderson P. Jones, Lilian Cha, Shelley Gorman, David A. Brown, Samuel N. Breit, Allan G. Kermode, Martyn A. French, Natalie C. Ward, Prue H. Hart
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84881-8