Overlapping variants in the blood, tissues and cell lines for patients with intracranial meningiomas are predominant in stem cell-related genes

Objective: Bulk tissue genomic analysis of meningiomas identified common somatic mutations, however, it often excluded blood-related variants. In contrast, genomic characterisation of primary cell lines that can provide critical information regarding growth and proliferation, have been rare. In our...

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Bibliographic Details
Main Authors: Deema Hussein, Ashraf Dallol, Rita Quintas, Hans-Juergen Schulten, Mona Alomari, Saleh Baeesa, Mohammed Bangash, Fahad Alghamdi, Ishaq Khan, M-Zaki Mustafa ElAssouli, Mohamad Saka, Angel Carracedo, Adeel Chaudhary, Adel Abuzenadah
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020324750