TARGETING CD8 T CELL METABOLISM IN TRANSPLANTATION

TARGETING CD8 T CELL METABOLISM IN TRANSPLANTATION

Infiltration of effector CD8 T cells play a major role in allograft rejection, and increases in memory and terminally-differentiated effector memory (TEMRA) CD8 T cells are associated with long term allograft dysfunction. Alternatively, CD8 regulatory T (Tregs) cells suppress the inflammatory respon...

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Bibliographic Details
Main Authors: Michelle eYap, Sophie eBrouard, Claire ePecqueur, Nicolas eDegauque
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
Glycolysis
Metabolism
Mitochondria
Therapeutics
Transplantation Immunology
regulation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00547/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00547/full

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