Lack of Small Intestinal Dysbiosis Following Long-Term Selective Inhibition of Cyclooxygenase-2 by Rofecoxib in the Rat

Lack of Small Intestinal Dysbiosis Following Long-Term Selective Inhibition of Cyclooxygenase-2 by Rofecoxib in the Rat

Intestinal dysbiosis is linked to numerous gastrointestinal disorders, including inflammatory bowel diseases. It is a question of debate if coxibs, selective inhibitors of cyclooxygenase (COX)-2, cause dysbiosis. Therefore, in the present study, we aimed to determine the effect of long-term (four we...

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Bibliographic Details
Main Authors: Bernadette Lázár, Gábor B. Brenner, András Makkos, Mihály Balogh, Szilvia B. László, Mahmoud Al-Khrasani, Barbara Hutka, Emese Bató, Eszter Ostorházi, János Juhász, Ágnes Kemény, Terézia László, László Tiszlavicz, Zoltán Bihari, Zoltán Giricz, Dóra Szabó, Zsuzsanna Helyes, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
microbiota
intestinal dysbiosis
inflammatory bowel diseases
cyclooxygenase-2
rofecoxib
enteropathy
Online Access:http://www.mdpi.com/2073-4409/8/3/251

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http://www.mdpi.com/2073-4409/8/3/251

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