Ceramide Initiates NFκB-Mediated Caspase Activation in Neuronal Apoptosis

The objective of the present study was to evaluate the role of ceramide in mediating apoptosis of dorsal root ganglion neurons induced by either nerve growth factor withdrawal or treatment with the chemotherapeutic agents suramin and cisplatin. Measurement of ceramide accumulation by mass spectromet...

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Bibliographic Details
Main Authors: Jagjit S. Gill, Anthony J. Windebank
Format: Article
Language:English
Published: Elsevier 2000-08-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996100903127