Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice

Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice

The metabolism and generation of bioactive lipid mediators are key events in the exertion of the beneficial effects of dietary omega-3 fatty acids in the regulation of allergic inflammation. Here, we found that dietary linseed oil, which contains high amounts of alpha-linolenic acid (ALA) dampened a...

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Bibliographic Details
Main Authors: Kento Sawane, Takahiro Nagatake, Koji Hosomi, So-ichiro Hirata, Jun Adachi, Yuichi Abe, Junko Isoyama, Hidehiko Suzuki, Ayu Matsunaga, Satoshi Fukumitsu, Kazuhiko Aida, Takeshi Tomonaga, Makoto Aria, Jun Kunisawa
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Nutrients
Subjects:
omega-3 fatty acids
nasal allergy
eosinophil
lipid metabolism
ppar
Online Access:https://www.mdpi.com/2072-6643/11/12/2868

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https://www.mdpi.com/2072-6643/11/12/2868

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