The Potential Role of Lysosomal Sequestration in Sunitinib Resistance of Renal Cell Cancer

  Renal cell carcinoma (RCC) is a highly vascularized tumor type, which is often associated with inactivated mutations in the von Hippel-Lindau gene that drives proangiogenic signaling pathways. As such, new therapies for the treatment of RCC have largely been focused on blocking angiogenesis. Sun...

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Bibliographic Details
Main Authors: Kaamar Azijli, Kristy J Gotink, Henk M.W Verheul
Format: Article
Language:English
Published: Codon Publications 2016-01-01
Series:Journal of Kidney Cancer and VHL
Subjects:
Online Access:https://jkcvhl.com/index.php/jkcvhl/article/view/44