Design and rationale of a 16-week adjunctive randomized placebo-controlled trial of mitochondrial agents for the treatment of bipolar depression

Design and rationale of a 16-week adjunctive randomized placebo-controlled trial of mitochondrial agents for the treatment of bipolar depression

Objective: Bipolar disorder places a significant burden on individuals, caregivers and family, and the broader community. Current treatments are believed to be more effective against manic symptoms, leaving a shortfall in recovery during the depressive phase of the illness. The current study draws o...

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Bibliographic Details
Main Authors: Olivia M. Dean, Alyna Turner, Gin S. Malhi, Chee Ng, Sue M. Cotton, Seetal Dodd, Jerome Sarris, Yuval Samuni, Michelle Tanious, Nathan Dowling, Astrid Waterdrinker, Deidre Smith, Michael Berk
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2015-03-01
Series:Brazilian Journal of Psychiatry
Subjects:
Mitochondria
bipolar disorder
depression
acetylcysteine
oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462015000100003&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462015000100003&lng=en&tlng=en

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