Impact of Mononuclear Cell Infiltration on Chondrodestructive MMP/ADAMTS Production in Osteoarthritic Knee Joints—An Ex Vivo Study

Progressive loss of joint function in osteoarthritis (OA) is driven by degenerative and inflammatory processes and their complex interaction. Decoding the link between degeneration and inflammation is one of the most exciting approaches in understanding OA pathophysiology and holds the promise to op...

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Bibliographic Details
Main Authors: Hadrian Platzer, Timo A. Nees, Tobias Reiner, Elena Tripel, Simone Gantz, Sébastien Hagmann, Babak Moradi, Nils Rosshirt
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
MMP
Online Access:https://www.mdpi.com/2077-0383/9/5/1279