Large genomic fragment deletions and insertions in mouse using CRISPR/Cas9.

Large genomic fragment deletions and insertions in mouse using CRISPR/Cas9.

ZFN, TALENs and CRISPR/Cas9 system have been used to generate point mutations and large fragment deletions and insertions in genomic modifications. CRISPR/Cas9 system is the most flexible and fast developing technology that has been extensively used to make mutations in all kinds of organisms. Howev...

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Bibliographic Details
Main Authors: Luqing Zhang, Ruirui Jia, Norberto J Palange, Achim Cchitvsanzwhoh Satheka, Jacques Togo, Yao An, Mabwi Humphrey, Luying Ban, Yan Ji, Honghong Jin, Xuechao Feng, Yaowu Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4372442?pdf=render

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http://europepmc.org/articles/PMC4372442?pdf=render

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