Complex I inhibition in the visual pathway induces disorganization of the node of Ranvier

Mitochondrial defects can have significant consequences on many aspects of neuronal physiology. In particular, deficiencies in the first enzyme complex of the mitochondrial respiratory chain (complex I) are considered to be involved in a number of human neurodegenerative diseases. The current work h...

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Bibliographic Details
Main Authors: Mathieu Marella, Gaurav Patki, Akemi Matsuno-Yagi, Takao Yagi
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113001848