Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo

Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo

Summary: Definitive hematopoietic stem cells (HSCs) first emerge in the aorta-gonad-mesonephros (AGM) region in both mice and humans. An ex vivo culture approach has enabled recapitulation and analysis of murine HSC development. Knowledge of early human HSC development is hampered by scarcity of tis...

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Bibliographic Details
Main Authors: Jennifer Easterbrook, Stanislav Rybtsov, Sabrina Gordon-Keylock, Andrejs Ivanovs, Samir Taoudi, Richard A. Anderson, Alexander Medvinsky
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119300888

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http://www.sciencedirect.com/science/article/pii/S2213671119300888

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