Cytoplasmic expression of LGR5 in pancreatic adenocarcinoma.

Cytoplasmic expression of LGR5 in pancreatic adenocarcinoma.

Background: CD133 has been identified as a cancer stem cell (CSC) marker for pancreatic ductal adenocarcinoma. Although leucine-rich-repeat-containing G-protein-coupled receptor 5 (LGR5), a marker of intestinal stem cells, has been shown to be on a higher level of the stem cell hierarchy than CD133,...

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Bibliographic Details
Main Authors: Nobumasa eMizuno, Yasushi eYatabe, Kazuo eHara, Susumu eHijioka, Hiroshi eImaoka, Yasuhiro eShimizu, Shigeru B.H. Ko, Kenji eYamao
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Physiology
Subjects:
Cytoplasm
Endocrine Cells
cancer stem cells
CD133
LGR5
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00269/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00269/full

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