Peripheral Delta Opioid Receptors Mediate Formoterol Anti-allodynic Effect in a Mouse Model of Neuropathic Pain

Peripheral Delta Opioid Receptors Mediate Formoterol Anti-allodynic Effect in a Mouse Model of Neuropathic Pain

Neuropathic pain is a challenging condition for which current therapies often remain unsatisfactory. Chronic administration of β2 adrenergic agonists, including formoterol currently used to treat asthma and chronic obstructive pulmonary disease, alleviates mechanical allodynia in the sciatic nerve c...

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Bibliographic Details
Main Authors: Rhian Alice Ceredig, Florian Pierre, Stéphane Doridot, Unai Alduntzin, Pierre Hener, Eric Salvat, Ipek Yalcin, Claire Gaveriaux-Ruff, Michel Barrot, Dominique Massotte
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
mechanical allodynia
beta-mimetics
peripheral nerve injury
cuff model
delta opioid receptor
beta adrenergic receptor
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00324/full

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https://www.frontiersin.org/article/10.3389/fnmol.2019.00324/full

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