3,6-Disubstituted 1,2,4-Triazolo[3,4-b]Thiadiazoles with Anticancer Activity Targeting Topoisomerase II Alpha

3,6-Disubstituted 1,2,4-Triazolo[3,4-b]Thiadiazoles with Anticancer Activity Targeting Topoisomerase II Alpha

Sofia Sagredou,1 Panagiotis Dalezis,1 Nikolaos Nikoleousakos,1 Michail Nikolaou,1 Maria Voura,2 Konstantinos Almpanakis,2 Mihalis I Panayiotidis,3,4 Vasiliki Sarli,2 Dimitrios T Trafalis1 1Laboratory of Pharmacology, Faculty of Medicine, National and Kapodistrian University of Athens, Athens 11527,...

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Bibliographic Details
Main Authors: Sagredou S, Dalezis P, Nikoleousakos N, Nikolaou M, Voura M, Almpanakis K, Panayiotidis MI, Sarli V, Trafalis DT
Format: Article
Language:English
Published: Dove Medical Press 2020-07-01
Series:OncoTargets and Therapy
Subjects:
triazoles
thiadiazoles
topoisomerase iiα
catalytic cycle
ser-1106
phosphorylation
Online Access:https://www.dovepress.com/36-disubstituted-124-triazolo34-bthiadiazoles-with-anticancer-activity-peer-reviewed-article-OTT

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https://www.dovepress.com/36-disubstituted-124-triazolo34-bthiadiazoles-with-anticancer-activity-peer-reviewed-article-OTT

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