Impact of CYP2C19 polymorphisms on serum concentration of voriconazole in iranian hematological patients

Impact of CYP2C19 polymorphisms on serum concentration of voriconazole in iranian hematological patients

Objective: This study aimed to determine the portion of Iranian patients who attain therapeutic serum concentrations of voriconazole (VRCZ) following administration of fixed doses. In addition, the effect of CYP2C19 polymorphism on serum levels of VRCZ was also investigated. Methods: Forty-eight adu...

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Bibliographic Details
Main Authors: Sholeh Ebrahimpour, Soha Namazi, Mehdi Mohammadi, Mohsen Nikbakht, Molouk Hadjibabaie, Hamidreza Taghvaye Masoumi, Ardeshir Ghavamzadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Research in Pharmacy Practice
Subjects:
CYP2C19 polymorphism
Iran
therapeutic drug monitoring
Voriconazole
Online Access:http://www.jrpp.net/article.asp?issn=2319-9644;year=2017;volume=6;issue=3;spage=151;epage=157;aulast=Ebrahimpour

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http://www.jrpp.net/article.asp?issn=2319-9644;year=2017;volume=6;issue=3;spage=151;epage=157;aulast=Ebrahimpour

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