Arrestins: structural disorder creates rich functionality

Arrestins: structural disorder creates rich functionality

Abstract Arrestins are soluble relatively small 44–46 kDa proteins that specifically bind hundreds of active phosphorylated GPCRs and dozens of non-receptor partners. There are binding partners that demonstrate preference for each of the known arrestin conformations: free, receptor-bound, and microt...

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Bibliographic Details
Main Authors: Vsevolod V. Gurevich, Eugenia V. Gurevich, Vladimir N. Uversky
Format: Article
Language:English
Published: SpringerOpen 2018-02-01
Series:Protein & Cell
Subjects:
arrestin
GPCR
crystal structure
NMR
EPR
disorder
Online Access:http://link.springer.com/article/10.1007/s13238-017-0501-8

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http://link.springer.com/article/10.1007/s13238-017-0501-8

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