Arrestins: structural disorder creates rich functionality
Abstract Arrestins are soluble relatively small 44–46 kDa proteins that specifically bind hundreds of active phosphorylated GPCRs and dozens of non-receptor partners. There are binding partners that demonstrate preference for each of the known arrestin conformations: free, receptor-bound, and microt...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2018-02-01
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Series: | Protein & Cell |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1007/s13238-017-0501-8 |