Cheburator software for automatically calculating drug inhibitory concentrations from in vitro screening assays.

In the process of new cancer drug development, as the first step of their assessment, their activities are usually studied in vitro against a panel of cancer cell lines. The results of these in vitro drug screening assays are commonly expressed as inhibitory concentration 50% (IC50): the concentrati...

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Bibliographic Details
Main Author: Dmitry Nevozhay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153570?pdf=render