Formulation, Characterization and Evaluation against SH-SY5Y Cells of New Tacrine and Tacrine-MAP Loaded with Lipid Nanoparticles

Tacrine (TAC) was the first FDA approved drug for the treatment of Alzheimer’s disease, resulting in increased memory and enhanced cognitive symptoms in patients. However, long-term therapy presents poor patient compliance associated with undesired side effects such as nausea, vomiting and hepatoxic...

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Bibliographic Details
Main Authors: Sara Silva, Joana Marto, Lídia Gonçalves, António J. Almeida, Nuno Vale
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Nanomaterials
Subjects:
MAP
Online Access:https://www.mdpi.com/2079-4991/10/10/2089