Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis.

BACKGROUND: Understanding the biogenesis pathways for the functional expression of recombinant proteins, in particular membrane proteins and complex multidomain assemblies, is a fundamental issue in cell biology and of high importance for future progress in structural genomics. In this study, we emp...

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Bibliographic Details
Main Authors: Ravi K R Marreddy, Eric R Geertsma, Hjalmar P Permentier, Joao P C Pinto, Jan Kok, Bert Poolman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2859938?pdf=render