Resistance to Chronic Toxoplasma gondii Infection Induced by a DNA Vaccine Expressing GRA16

Toxoplasma gondii can infect all warm-blooded animals including human beings. T. gondii dense granule protein 16 (TgGRA16) as a crucial virulence factor could modulate the host gene expression. Here, a DNA vaccine expressing TgGRA16 was constructed to explore the protective efficacy against T. gondi...

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Bibliographic Details
Main Authors: Ling-Ying Hu, Nian-Zhang Zhang, Fu-Kai Zhang, Meng Wang, Qi Gao, Jin-Lei Wang, Xing-Quan Zhu
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/1295038