Lipoteichoic acid induces surfactant protein-A biosynthesis in human alveolar type II epithelial cells through activating the MEK1/2-ERK1/2-NF-κB pathway

Lipoteichoic acid induces surfactant protein-A biosynthesis in human alveolar type II epithelial cells through activating the MEK1/2-ERK1/2-NF-κB pathway

<p>Abstract</p> <p>Background</p> <p>Lipoteichoic acid (LTA), a gram-positive bacterial outer membrane component, can cause septic shock. Our previous studies showed that the gram-negative endotoxin, lipopolysaccharide (LPS), could induce surfactant protein-A (SP-A) pro...

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Bibliographic Details
Main Authors: Liu Feng-Lin, Chuang Chi-Yuan, Tai Yu-Ting, Tang Hsiu-Lien, Chen Tyng-Guey, Chen Ta-Liang, Chen Ruei-Ming
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Respiratory Research
Subjects:
Lipoteichoic acid
Alveolar epithelial cells
Surfactant protein-A
MEK/ERK/NF-κB
Online Access:http://respiratory-research.com/content/13/1/88

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http://respiratory-research.com/content/13/1/88

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