Single-cell ATAC-seq signal extraction and enhancement with SCATE

Single-cell ATAC-seq signal extraction and enhancement with SCATE

Abstract Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) is the state-of-the-art technology for analyzing genome-wide regulatory landscapes in single cells. Single-cell ATAC-seq data are sparse and noisy, and analyzing such data is challenging. Existing computational m...

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Bibliographic Details
Main Authors: Zhicheng Ji, Weiqiang Zhou, Wenpin Hou, Hongkai Ji
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Genome Biology
Subjects:
Single cell
Chromatin
scATAC-seq
Bioinformatics
Statistical modeling
Machine learning
Online Access:http://link.springer.com/article/10.1186/s13059-020-02075-3

Internet

http://link.springer.com/article/10.1186/s13059-020-02075-3

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