Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development

Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development

Pituitary developmental defects lead to partial or complete hormone deficiency and significant health problems. The majority of cases are sporadic and of unknown cause. We screened 28 patients with pituitary stalk interruption syndrome for mutations in the FAT/DCHS family of protocadherins that have...

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Bibliographic Details
Main Authors: Emily J. Lodge, Paraskevi Xekouki, Tatiane S. Silva, Cristiane Kochi, Carlos A. Longui, Fabio R. Faucz, Alice Santambrogio, James L. Mills, Nathan Pankratz, John Lane, Dominika Sosnowska, Tina Hodgson, Amanda L. Patist, Philippa Francis-West, Françoise Helmbacher, Constantine A. Stratakis, Cynthia L. Andoniadou
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-12-01
Series:JCI Insight
Subjects:
Development
Endocrinology
Online Access:https://doi.org/10.1172/jci.insight.134310

Internet

https://doi.org/10.1172/jci.insight.134310

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