Heterochromatic genome stability requires regulators of histone H3 K9 methylation.
Heterochromatin contains many repetitive DNA elements and few protein-encoding genes, yet it is essential for chromosome organization and inheritance. Here, we show that Drosophila that lack the Su(var)3-9 H3K9 methyltransferase display significantly elevated frequencies of spontaneous DNA damage in...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-03-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2654965?pdf=render |